Metabolomics of the third culture of LN18 IDH1 mutant and wild-type cells
These data were produced from the analysis of the third culture of LN18 cells with (MUT) and without (WT) a transduced isocitrate dehydrogenase 1 (IDH1) mutation. The data were acquired as part of the project “Investigating Isocitrate Dehydrogenase Mutations in Cancer Using New Metabolomics Methods”...
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| Format: | Dataset |
| Idioma: | English |
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University of Oxford
2020
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| Sumari: | These data were produced from the analysis of the third culture of LN18 cells with (MUT) and without (WT) a transduced isocitrate dehydrogenase 1 (IDH1) mutation. The data were acquired as part of the project “Investigating Isocitrate Dehydrogenase Mutations in Cancer Using New Metabolomics Methods” using multiple liquid chromatography-mass spectrometry methods. Anion-exchange chromatography-mass spectrometry (IC-MS) data were acquired on a Dionex IC-5000+ ion chromatography system hyphenated to a Thermo Fisher Scientific Exactive. Reversed-phase chromatography-mass spectrometry (RP-MS) data were acquired on a Dionex U3000 UHPLC system hyphenated to a Thermo Fisher Scientific Exactive. Derivatised RP-MS data were acquired on a Dionex U3000 UHPLC system hyphenated to a Thermo Fisher Scientific Exactive with sample derivatisation using 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate.
Data are .zip compressed to reduce file size. Data files in the .RAW format require Thermo Fisher Scientific Xcalibur software to analyse. |
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