Label-free single molecule imaging with numerical aperture-shaped interferometric scattering microscopy

Our ability to optically interrogate nanoscopic objects is controlled by the difference between their extinction cross sections and the diffraction-limited area to which light can be confined in the far-field. Here, we show that a partially transmissive spatial mask placed near the back focal plane...

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Detalhes bibliográficos
Main Authors: Cole, D, Young, G, Weigel, A, Kukura, P
Formato: Journal article
Publicado em: American Chemical Society 2017