α-Amino bicycloalkylation through organophotoredox catalysis †

Bridged bicycloalkanes such as bicyclo[1.1.1]pentanes (BCPs) and bicyclo[3.1.1]heptanes (BCHeps) are important motifs in contemporary drug design due to their potential to act as bioisosteres of disubstituted benzene rings, often resulting in compounds with improved physicochemical and pharmacokinet...

Полное описание

Библиографические подробности
Главные авторы: Nugent, J, López-Francés, A, Sterling, AJ, Tay, MY, Frank, N, Mousseau, JJ, Duarte, F, Anderson, EA
Формат: Journal article
Язык:English
Опубликовано: Royal Society of Chemistry 2024