Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.

A double-site enzyme-linked lactate dehydrogenase enzyme immunodetection assay was tested against field isolates of Plasmodium falciparum for assessing in vitro drug susceptibilities to a wide range of antimalarial drugs. Its sensitivity allowed the use of parasite densities as low as 200 parasites/...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Brockman, A, Singlam, S, Phiaphun, L, Looareesuwan, S, White, N, Nosten, F
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2004
_version_ 1826260036757749760
author Brockman, A
Singlam, S
Phiaphun, L
Looareesuwan, S
White, N
Nosten, F
author_facet Brockman, A
Singlam, S
Phiaphun, L
Looareesuwan, S
White, N
Nosten, F
author_sort Brockman, A
collection OXFORD
description A double-site enzyme-linked lactate dehydrogenase enzyme immunodetection assay was tested against field isolates of Plasmodium falciparum for assessing in vitro drug susceptibilities to a wide range of antimalarial drugs. Its sensitivity allowed the use of parasite densities as low as 200 parasites/microl of blood. Being a nonisotopic, colorimetric assay, it lies within the capabilities of a modest laboratory at the district level.
first_indexed 2024-03-06T18:59:16Z
format Journal article
id oxford-uuid:12f3b760-a967-4acd-b129-09a3043e248c
institution University of Oxford
language English
last_indexed 2024-03-06T18:59:16Z
publishDate 2004
record_format dspace
spelling oxford-uuid:12f3b760-a967-4acd-b129-09a3043e248c2022-03-26T10:11:01ZField evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:12f3b760-a967-4acd-b129-09a3043e248cEnglishSymplectic Elements at Oxford2004Brockman, ASinglam, SPhiaphun, LLooareesuwan, SWhite, NNosten, FA double-site enzyme-linked lactate dehydrogenase enzyme immunodetection assay was tested against field isolates of Plasmodium falciparum for assessing in vitro drug susceptibilities to a wide range of antimalarial drugs. Its sensitivity allowed the use of parasite densities as low as 200 parasites/microl of blood. Being a nonisotopic, colorimetric assay, it lies within the capabilities of a modest laboratory at the district level.
spellingShingle Brockman, A
Singlam, S
Phiaphun, L
Looareesuwan, S
White, N
Nosten, F
Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title_full Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title_fullStr Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title_full_unstemmed Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title_short Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
title_sort field evaluation of a novel colorimetric method double site enzyme linked lactate dehydrogenase immunodetection assay to determine drug susceptibilities of plasmodium falciparum clinical isolates from northwestern thailand
work_keys_str_mv AT brockmana fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand
AT singlams fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand
AT phiaphunl fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand
AT looareesuwans fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand
AT whiten fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand
AT nostenf fieldevaluationofanovelcolorimetricmethoddoublesiteenzymelinkedlactatedehydrogenaseimmunodetectionassaytodeterminedrugsusceptibilitiesofplasmodiumfalciparumclinicalisolatesfromnorthwesternthailand