Calculation of carcinogenic potency from long-term animal carcinogenesis experiments.

An index of carcinogenic potency for chemicals tested in chronic animal experiments is described. By analogy with the well-known 'lethal dose 50' (LD50) of quantal bioassay, a 'tumorigenic dose 50' (TD50) may be defined (in the absence both of tumors in the control group and of i...

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Detalhes bibliográficos
Main Authors: Sawyer, C, Peto, R, Bernstein, L, Pike, M
Formato: Journal article
Idioma:English
Publicado em: 1984