Pathogen recognition or homeostasis? APC receptor functions in innate immunity.
Myeloid cells (macrophages, neutrophils, dendritic cells) express a repertoire of plasma membrane receptors able to recognize all classes of macromolecules. The concept of pattern recognition has emphasized microbial ligands and host defence. However, these receptors play a broader role in tissue ho...
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| Format: | Conference item |
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2004
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| _version_ | 1826260048939057152 |
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| author | Gordon, S |
| author_facet | Gordon, S |
| author_sort | Gordon, S |
| collection | OXFORD |
| description | Myeloid cells (macrophages, neutrophils, dendritic cells) express a repertoire of plasma membrane receptors able to recognize all classes of macromolecules. The concept of pattern recognition has emphasized microbial ligands and host defence. However, these receptors play a broader role in tissue homeostasis within multicellular hosts, clearing the extracellular environment of potential undesirable ligands arising endogenously as well as from without. This article will evaluate one of the paradigms that underlie innate immunity. |
| first_indexed | 2024-03-06T18:59:26Z |
| format | Conference item |
| id | oxford-uuid:13029597-7165-4c02-bcf9-2fbaf446ecb2 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T18:59:26Z |
| publishDate | 2004 |
| record_format | dspace |
| spelling | oxford-uuid:13029597-7165-4c02-bcf9-2fbaf446ecb22022-03-26T10:11:20ZPathogen recognition or homeostasis? APC receptor functions in innate immunity.Conference itemhttp://purl.org/coar/resource_type/c_5794uuid:13029597-7165-4c02-bcf9-2fbaf446ecb2Symplectic Elements at Oxford2004Gordon, SMyeloid cells (macrophages, neutrophils, dendritic cells) express a repertoire of plasma membrane receptors able to recognize all classes of macromolecules. The concept of pattern recognition has emphasized microbial ligands and host defence. However, these receptors play a broader role in tissue homeostasis within multicellular hosts, clearing the extracellular environment of potential undesirable ligands arising endogenously as well as from without. This article will evaluate one of the paradigms that underlie innate immunity. |
| spellingShingle | Gordon, S Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title | Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title_full | Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title_fullStr | Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title_full_unstemmed | Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title_short | Pathogen recognition or homeostasis? APC receptor functions in innate immunity. |
| title_sort | pathogen recognition or homeostasis apc receptor functions in innate immunity |
| work_keys_str_mv | AT gordons pathogenrecognitionorhomeostasisapcreceptorfunctionsininnateimmunity |