Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.

Hepatoblastoma is the most common primary liver tumor in childhood and occurs more commonly in families with familial adenomatous polyposis. Germline mutations of the gene responsible for familial adenomatous polyposis--adenomatous polyposis coli (APC)--are described in patients with hepatoblastoma...

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Bibliographic Details
Main Authors: Harvey, J, Clark, S, Hyer, W, Hadzic, N, Tomlinson, I, Hinds, R
Format: Journal article
Language:English
Published: 2008