Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.

Hepatoblastoma is the most common primary liver tumor in childhood and occurs more commonly in families with familial adenomatous polyposis. Germline mutations of the gene responsible for familial adenomatous polyposis--adenomatous polyposis coli (APC)--are described in patients with hepatoblastoma...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Harvey, J, Clark, S, Hyer, W, Hadzic, N, Tomlinson, I, Hinds, R
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2008