Targeting vascular endothelial growth factor receptor-1 and -3 with cediranib (AZD2171): effects on migration and invasion of gastrointestinal cancer cell lines.
The effect of vascular endothelial growth factor (VEGF) ligands and cediranib on tumor cell proliferation, migration, and invasion was determined. It has recently been suggested that autocrine signaling through the VEGF receptor (VEGFR) pathway may play a role in tumor cell survival, invasion, and m...
Main Authors: | Morelli, M, Brown, A, Pitts, T, Tentler, J, Ciardiello, F, Ryan, A, Jürgensmeier, J, Eckhardt, S |
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Format: | Journal article |
Language: | English |
Published: |
2009
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