Regiodivergent nucleophilic fluorination under hydrogen bonding catalysis: a computational and experimental study

The controlled programming of regiochemical outcomes in nucleophilic fluorination reactions with alkali metal fluoride is a problem yet to be solved. Herein, two synergistic approaches exploiting hydrogen bonding catalysis are presented. First, we demonstrate that modulating the charge density of fl...

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Những tác giả chính: Horwitz, MA, Dürr, AB, Afratis, K, Chen, Z, Soika, J, Christensen, KE, Fushimi, M, Paton, RS, Gouverneur, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: American Chemical Society 2023