Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.
Levels of anti-inflammatory extracellular adenosine are controlled by the sequential action of the ectonucleotidases CD39 and CD73, whose expression in CD4(+) T cells has been associated with natural regulatory T cells (nTregs). We here show that CD73 expression on activated murine CD4(+) T cells is...
Principais autores: | Regateiro, F, Howie, D, Nolan, K, Agorogiannis, E, Greaves, D, Cobbold, S, Waldmann, H |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2011
|
Registros relacionados
-
Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.
por: Regateiro, F, et al.
Publicado em: (2011) -
Anti-inflammatory peripheral adenosine generation by leukocytes is tightly regulated by TGF-beta and is independent of Foxp3
por: Regateiro, F, et al.
Publicado em: (2010) -
TGF-β in transplantation tolerance.
por: Regateiro, F, et al.
Publicado em: (2011) -
TGF-β in transplantation tolerance
por: Regateiro, F, et al.
Publicado em: (2011) -
CD73 and adenosine generation in the creation of regulatory microenvironments.
por: Regateiro, F, et al.
Publicado em: (2013)