Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.

Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.

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Levels of anti-inflammatory extracellular adenosine are controlled by the sequential action of the ectonucleotidases CD39 and CD73, whose expression in CD4(+) T cells has been associated with natural regulatory T cells (nTregs). We here show that CD73 expression on activated murine CD4(+) T cells is...

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Библиографические подробности
Главные авторы:	Regateiro, F, Howie, D, Nolan, K, Agorogiannis, E, Greaves, D, Cobbold, S, Waldmann, H
Формат:	Journal article
Язык:	English
Опубликовано:	2011

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