Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.

Levels of anti-inflammatory extracellular adenosine are controlled by the sequential action of the ectonucleotidases CD39 and CD73, whose expression in CD4(+) T cells has been associated with natural regulatory T cells (nTregs). We here show that CD73 expression on activated murine CD4(+) T cells is...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Regateiro, F, Howie, D, Nolan, K, Agorogiannis, E, Greaves, D, Cobbold, S, Waldmann, H
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2011