CD52-Negative NK cells are abundant in the liver and less susceptible to alemtuzumab treatment

<strong>Background</strong> T-cell depleting strategies have become an integral part of immunosuppressive regimens in organ transplantation. Alemtuzumab is a humanized monoclonal antibody against CD52, a cell-surface antigen on several immune cells. It has been suggested that lymphocyte...

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Bibliographic Details
Main Authors: Hotta, R, Ohira, M, Matsuura, T, Muraoka, I, Tryphonopoulos, P, Fan, J, Tekin, A, Selvaggi, G, Levi, D, Ruiz, P, Ricordi, C, Vianna, R, Ohdan, H, Waldmann, H, Tzakis, A, Nishida, S
Format: Journal article
Language:English
Published: Public Library of Science 2016