Pathways for glycoprotein degradation in mammalian cells

In mammalian cells, N-glycoproteins comprise the bulk of secretory cargo. N-glycosylation is tightly linked to the mechanisms of co- and post-translational folding and quality control in the endoplasmic reticulum (ER). Aberrant glycoproteins must be cleared from the secretory pathway. Several mechan...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Kukushkin, N, Nikolay Kukushkin
Andre forfattere: Butters, T
Format: Thesis
Sprog:English
Udgivet: 2011
Fag: