Pathways for glycoprotein degradation in mammalian cells

In mammalian cells, N-glycoproteins comprise the bulk of secretory cargo. N-glycosylation is tightly linked to the mechanisms of co- and post-translational folding and quality control in the endoplasmic reticulum (ER). Aberrant glycoproteins must be cleared from the secretory pathway. Several mechan...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Kukushkin, N, Nikolay Kukushkin
Weitere Verfasser: Butters, T
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2011
Schlagworte: