Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: UK Heart and Renal Protection (UK HARP)-III. Rationale, trial design and baseline data

<p>Background: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the natriuretic peptide system) may reduce these ri...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Haynes, R, Judge, P
التنسيق: Journal article
منشور في: Oxford University Press 2016