A1C to detect diabetes in healthy adults: when should we recheck?
OBJECTIVE: To evaluate the optimal interval for rechecking A1C levels below the diagnostic threshold of 6.5% for healthy adults. RESEARCH DESIGN AND METHODS: This was a retrospective cohort study. Participants were 16,313 apparently healthy Japanese adults not taking glucose-lowering medications at...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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| _version_ | 1797054684134899712 |
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| author | Takahashi, O Farmer, A Shimbo, T Fukui, T Glasziou, P |
| author_facet | Takahashi, O Farmer, A Shimbo, T Fukui, T Glasziou, P |
| author_sort | Takahashi, O |
| collection | OXFORD |
| description | OBJECTIVE: To evaluate the optimal interval for rechecking A1C levels below the diagnostic threshold of 6.5% for healthy adults. RESEARCH DESIGN AND METHODS: This was a retrospective cohort study. Participants were 16,313 apparently healthy Japanese adults not taking glucose-lowering medications at baseline. Annual A1C measures from 2005 to 2008 at the Center for Preventive Medicine, a community teaching hospital in Japan, estimated cumulative incidence of diabetes. RESULTS: Mean age (+/-SD) of participants was 49.7 +/- 12.3 years, and 53% were male. Mean A1C at baseline was 5.4 +/- 0.5%. At 3 years, for those with A1C at baseline of <5.0%, 5.0-5.4%, 5.5-5.9%, and 6.0-6.4%, cumulative incidence (95% CI) was 0.05% (0.001-0.3), 0.05% (0.01-0.11), 1.2% (0.9-1.6), and 20% (18-23), respectively. CONCLUSIONS: In those with an A1C <6.0%, rescreening at intervals shorter than 3 years identifies few individuals (approximately <or=1%) a1c="" an="" with="">or=6.5%.</or=1%)> |
| first_indexed | 2024-03-06T19:00:42Z |
| format | Journal article |
| id | oxford-uuid:136c2922-9b1e-4b97-bd43-c9769748201a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:00:42Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:136c2922-9b1e-4b97-bd43-c9769748201a2022-03-26T10:13:48ZA1C to detect diabetes in healthy adults: when should we recheck?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:136c2922-9b1e-4b97-bd43-c9769748201aEnglishSymplectic Elements at Oxford2010Takahashi, OFarmer, AShimbo, TFukui, TGlasziou, P OBJECTIVE: To evaluate the optimal interval for rechecking A1C levels below the diagnostic threshold of 6.5% for healthy adults. RESEARCH DESIGN AND METHODS: This was a retrospective cohort study. Participants were 16,313 apparently healthy Japanese adults not taking glucose-lowering medications at baseline. Annual A1C measures from 2005 to 2008 at the Center for Preventive Medicine, a community teaching hospital in Japan, estimated cumulative incidence of diabetes. RESULTS: Mean age (+/-SD) of participants was 49.7 +/- 12.3 years, and 53% were male. Mean A1C at baseline was 5.4 +/- 0.5%. At 3 years, for those with A1C at baseline of <5.0%, 5.0-5.4%, 5.5-5.9%, and 6.0-6.4%, cumulative incidence (95% CI) was 0.05% (0.001-0.3), 0.05% (0.01-0.11), 1.2% (0.9-1.6), and 20% (18-23), respectively. CONCLUSIONS: In those with an A1C <6.0%, rescreening at intervals shorter than 3 years identifies few individuals (approximately <or=1%) a1c="" an="" with="">or=6.5%.</or=1%)> |
| spellingShingle | Takahashi, O Farmer, A Shimbo, T Fukui, T Glasziou, P A1C to detect diabetes in healthy adults: when should we recheck? |
| title | A1C to detect diabetes in healthy adults: when should we recheck? |
| title_full | A1C to detect diabetes in healthy adults: when should we recheck? |
| title_fullStr | A1C to detect diabetes in healthy adults: when should we recheck? |
| title_full_unstemmed | A1C to detect diabetes in healthy adults: when should we recheck? |
| title_short | A1C to detect diabetes in healthy adults: when should we recheck? |
| title_sort | a1c to detect diabetes in healthy adults when should we recheck |
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