Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, genetic inheritance is a major component to risk. Previously, rare mutations in low-density lipoprotein (LDL) genes have been shown to contribute to MI risk...
Main Authors: | Do, R, Stitziel, N, Won, H, Jørgensen, AB, Duga, S, Angelica Merlini, P, Kiezun, A, Farrall, M, Goel, A, Zuk, O, Guella, I, Asselta, R, Lange, L, Peloso, G, Auer, P, Girelli, D, Martinelli, N, Farlow, D, DePristo, M, Roberts, R, Stewart, A, Saleheen, D, Danesh, J, Epstein, SE, Sivapalaratnam, S |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2014
|
פריטים דומים
-
Inactivating mutations in NPC1L1 and protection from coronary heart disease.
מאת: Stitziel, N, et al.
יצא לאור: (2014) -
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
מאת: Lander, Eric Steven
יצא לאור: (2017) -
Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.
מאת: Aenne S Thormaehlen, et al.
יצא לאור: (2015-02-01) -
Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction
מאת: Thormaehlen, Aenne S., et al.
יצא לאור: (2015) -
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
מאת: Crosby, J, et al.
יצא לאור: (2014)