Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, genetic inheritance is a major component to risk. Previously, rare mutations in low-density lipoprotein (LDL) genes have been shown to contribute to MI risk...
Автори: | Do, R, Stitziel, N, Won, H, Jørgensen, AB, Duga, S, Angelica Merlini, P, Kiezun, A, Farrall, M, Goel, A, Zuk, O, Guella, I, Asselta, R, Lange, L, Peloso, G, Auer, P, Girelli, D, Martinelli, N, Farlow, D, DePristo, M, Roberts, R, Stewart, A, Saleheen, D, Danesh, J, Epstein, SE, Sivapalaratnam, S |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2014
|
Схожі ресурси
Схожі ресурси
-
Inactivating mutations in NPC1L1 and protection from coronary heart disease.
за авторством: Stitziel, N, та інші
Опубліковано: (2014) -
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
за авторством: Lander, Eric Steven
Опубліковано: (2017) -
Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.
за авторством: Aenne S Thormaehlen, та інші
Опубліковано: (2015-02-01) -
Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction
за авторством: Thormaehlen, Aenne S., та інші
Опубліковано: (2015) -
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
за авторством: Crosby, J, та інші
Опубліковано: (2014)