Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation

Pericentrin is a conserved centrosomal protein whose dysfunction has been linked to several human diseases. It has been implicated in many aspects of centrosome and cilia function, but its precise role is unclear. Here, we examine Drosophila Pericentrin-like-protein (PLP) function in vivo in tissues...

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Detalhes bibliográficos
Principais autores: Roque, H, Saurya, S, Pratt, M, Johnson, E, Raff, J
Formato: Journal article
Publicado em: Public Library of Science 2018