Up-regulation of vascular cyclooxygenase-2 in diabetes mellitus.

Up-regulation of vascular cyclooxygenase-2 in diabetes mellitus.

Diabetes mellitus is associated with disturbed regulation in the microcirculation. A low-grade vascular inflammation has been implicated in the development of diabetes-related vascular complications, but the underlying molecular mechanisms has not yet been fully elucidated. It is known that cyclooxy...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Bagi, Z, Erdei, N, Papp, Z, Edes, I, Koller, A
Ձևաչափ:	Journal article
Լեզու:	English
Հրապարակվել է:	2006

Նմանատիպ նյութեր

Diabetes mellitus alters the intrinsic constrictor and dilator mechanisms regulating the tone of human coronary microvessels: Role of cyclooxygenase-2
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Increased cyclooxygenase-2 expression and prostaglandin-mediated dilation in coronary arterioles of patients with diabetes mellitus.
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Հրապարակվել է: (2006)

Multiple effects of diabetes mellitus on the vasomotor responses of human coronary arterioles
‌: Bagi, Z, և այլն
Հրապարակվել է: (2007)

Interaction between hydrogen peroxide and prostaglandin metabolism leads to microvascular dysfunction in type 2 diabetes mellitus
‌: Bagi, Z, և այլն
Հրապարակվել է: (2006)

Thromboxane A(2) contributes to the mediation of flow-induced responses of skeletal muscle venules: role of cyclooxygenases 1 and 2.
‌: Racz, A, և այլն
Հրապարակվել է: (2009)

H2O2 increases production of constrictor prostaglandins in smooth muscle leading to enhanced arteriolar tone in Type 2 diabetic mice.
‌: Erdei, N, և այլն
Հրապարակվել է: (2007)

Hydrogen peroxide elicits COX-2-dependent production of constrictor prostaglandins in arterioles of type 2 diabetic mice
‌: Bagi, Z, և այլն
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Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes.
‌: Rutkai, I, և այլն
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High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion.
‌: Erdei, N, և այլն
Հրապարակվել է: (2006)

Obesity-induced reduction in nitric oxide-dependent arteriolar dilation in rats. Role of xanthine oxidase-derived superoxide.
‌: Erdei, N, և այլն
Հրապարակվել է: (2006)

The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arterioles.
‌: Erdei, N, և այլն
Հրապարակվել է: (2006)

The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arterioles.
‌: Erdei, N, և այլն
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Increased soluble guanylate cyclase (sGC) activity may compensate for the high fat diet-induced reduction in NO bioavailability of rat coronary arterioles
‌: Koller, A, և այլն
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High intraluminal pressure via increased release of hydrogen peroxide maintains arteriolar responsiveness to angiotensin II
‌: Koller, A, և այլն
Հրապարակվել է: (2007)

Oxidative stress via activating soluble guanylate cyclase leads to increased nitric oxide sensitivity of coronary arterioles in high fat diet-induced obesity
‌: Erdei, N, և այլն
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High intraluminal pressure reduces tachyphylaxis to angiotensin II in isolated arterioles
‌: Koller, A, և այլն
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PPAR gamma activation improves wall shear stress dependent regulation of coronary arteriolar diameter in type 2 diabetes mellitus
‌: Bagi, Z, և այլն
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Specific roles of COX-1 and COX-2 inhibitors to interfere with the regulation of microvascular resistance in normal mice and mice with type 2 diabetes mellitus
‌: Bagi, Z, և այլն
Հրապարակվել է: (2005)

Cyclooxygenase-2 derived thromboxane A(2) and reactive oxygen species mediate flow-induced constrictions of venules in hyperhomocysteinemia.
‌: Racz, A, և այլն
Հրապարակվել է: (2010)

High intraluminal pressure via H2O2 upregulates arteriolar constrictions to angiotensin II by increasing the functional availability of AT1 receptors.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2008)

Adaptation of vasomotor function of human coronary arterioles to the simultaneous presence of obesity and hypertension.
‌: Fulop, T, և այլն
Հրապարակվել է: (2007)

Adaptation of coronary arteriolar dilations to the simultaneous presence of obesity and hypertension: Role of increased nitric oxide sensitivity
‌: Bagi, Z, և այլն
Հրապարակվել է: (2007)

P.034 THE INFLUENCE OF GENDER, CYCLOOXYGENASE-2 INHIBITION, AND HYPERGLYCEMIA ON VASCULAR FUNCTION IN UNCOMPLICATED TYPE 1 DIABETES MELLITUS
‌: D.Z.I. Cherney, և այլն
Հրապարակվել է: (2007-08-01)

PPAR gamma activation restores NO-Mediated dilations of coronary Arterioles in type 2 diabetes Mellitus
‌: Bagi, Z, և այլն
Հրապարակվել է: (2003)

Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1.
‌: Kark, T, և այլն
Հրապարակվել է: (2008)

Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2003)

Enhanced superoxide production reduces NO-mediation of flow-dependent dilation of isolated coronary arteries in type 2 diabetes mellitus
‌: Bagi, Z, և այլն
Հրապարակվել է: (2003)

The role of cycloxygenase-1 and-2 (COX-1,-2) in mediation of flow-induced responses of venules
‌: Racz, A, և այլն
Հրապարակվել է: (2009)

Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2005)

High intraluminal pressure reduces AT1 receptor internalization and maintains arteriolar constrictions to angiotensin II
‌: Koller, A, և այլն
Հրապարակվել է: (2007)

High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation.
‌: Jebelovszki, E, և այլն
Հրապարակվել է: (2008)

Intrinsic vascular mechanisms stimulated by changes in pressure and now elicit reactive dilatation of isolated arterioles
‌: Bagi, Z, և այլն
Հրապարակվել է: (2000)

Role of polyol pathway in oxidative stress-induced arteriolar dysfunction in diabetes mellitus (DM)
‌: Koller, A, և այլն
Հրապարակվել է: (2005)

Highlights of the 25th Conference of the European Society for Microcirculation: Integrating vascular biology and medicine: Basic and clinical science August 26-29, 2008, Budapest, Hungary
‌: Koller, A, և այլն
Հրապարակվել է: (2009)

Impaired NO-mediation of flow dependent arteriolar dilation in diabetes due to reduced level of tetrahydrobiopterin
‌: Bagi, Z, և այլն
Հրապարակվել է: (2002)

Type 2 diabetic mice have increased blood pressure and enhanced arteriolar basal tone due to COX-2-dependent TxA(2)/PGH(2) production
‌: Bagi, Z, և այլն
Հրապարակվել է: (2004)

Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2003)

PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2004)

Cyclooxygenase-2 and its regulation in inflammation
‌: Y. S. Bakhle, և այլն
Հրապարակվել է: (1996-01-01)

Preserved coronary arteriolar dilatation in patients with type 2 diabetes mellitus: implications for reactive oxygen species.
‌: Bagi, Z, և այլն
Հրապարակվել է: (2009)