Derivation of the bidomain equations for a beating heart with a general microstructure

A novel multiple scales method is formulated that can be applied to problems which have an almost periodic microstructure not in Cartesian coordinates but in a general curvilinear coordinate system. The method is applied to a model of the electrical activity of cardiac myocytes and used to derive a...

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主要作者: Chapman, S
格式: Journal article
出版: 2013
實物特徵
總結:A novel multiple scales method is formulated that can be applied to problems which have an almost periodic microstructure not in Cartesian coordinates but in a general curvilinear coordinate system. The method is applied to a model of the electrical activity of cardiac myocytes and used to derive a version of the bidomain equations describing the macroscopic electrical activity of cardiac tissue. The treatment systematically accounts for the non-uniform orientation of the cells within the tissue and for deformations of the tissue occurring as a result of the heart beat.