The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis

This systematic review aimed to evaluate the effects of therapeutic exercise on physical and psychosocial outcomes in community-dwelling adults aged 80 years or older. Databases were searched from inception to July 8, 2020. Randomized controlled trials (RCTs) were screened by two reviewers who extra...

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Main Authors: Nicolson, PJA, Duong, V, Williamson, E, Hopewell, S, Lamb, SE
Format: Journal article
Language:English
Published: Human Kinetics 2021
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author Nicolson, PJA
Duong, V
Williamson, E
Hopewell, S
Lamb, SE
author_facet Nicolson, PJA
Duong, V
Williamson, E
Hopewell, S
Lamb, SE
author_sort Nicolson, PJA
collection OXFORD
description This systematic review aimed to evaluate the effects of therapeutic exercise on physical and psychosocial outcomes in community-dwelling adults aged 80 years or older. Databases were searched from inception to July 8, 2020. Randomized controlled trials (RCTs) were screened by two reviewers who extracted data and assessed study quality. Sixteen RCTs (1,660 participants) were included. Compared to nonexercise controls there was no evidence of an effect of exercise on performance based (standardized mean differences: 0.58, 95% confidence interval: [−0.19, 1.36]; I 2: 89%; six RCTs; 290 participants; very low-quality evidence) or self-reported physical function (standardized mean differences: 1.35, 95% confidence interval: [−0.78, 3.48]; I 2: 96%; three RCTs; 280 participants; very low-quality evidence) at short-medium term follow-up. Four RCTs reporting psychosocial outcomes could not be combined in meta-analysis and reported varying results. Exercise appeared to reduce the risk of mortality during follow-up (risk ratio: 0.47, 95% confidence interval: [0.32, 0.70]; I 2: 0.0%; six RCTs; 1,222 participants; low-quality evidence).
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spelling oxford-uuid:13cb00f9-b3ae-45b9-bb96-e5e5583344042022-06-09T08:16:51ZThe effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:13cb00f9-b3ae-45b9-bb96-e5e558334404EnglishSymplectic ElementsHuman Kinetics2021Nicolson, PJADuong, VWilliamson, EHopewell, SLamb, SEThis systematic review aimed to evaluate the effects of therapeutic exercise on physical and psychosocial outcomes in community-dwelling adults aged 80 years or older. Databases were searched from inception to July 8, 2020. Randomized controlled trials (RCTs) were screened by two reviewers who extracted data and assessed study quality. Sixteen RCTs (1,660 participants) were included. Compared to nonexercise controls there was no evidence of an effect of exercise on performance based (standardized mean differences: 0.58, 95% confidence interval: [−0.19, 1.36]; I 2: 89%; six RCTs; 290 participants; very low-quality evidence) or self-reported physical function (standardized mean differences: 1.35, 95% confidence interval: [−0.78, 3.48]; I 2: 96%; three RCTs; 280 participants; very low-quality evidence) at short-medium term follow-up. Four RCTs reporting psychosocial outcomes could not be combined in meta-analysis and reported varying results. Exercise appeared to reduce the risk of mortality during follow-up (risk ratio: 0.47, 95% confidence interval: [0.32, 0.70]; I 2: 0.0%; six RCTs; 1,222 participants; low-quality evidence).
spellingShingle Nicolson, PJA
Duong, V
Williamson, E
Hopewell, S
Lamb, SE
The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title_full The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title_fullStr The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title_full_unstemmed The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title_short The effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older: a systematic review and meta-analysis
title_sort effect of therapeutic exercise interventions on physical and psychosocial outcomes in adults aged 80 years and older a systematic review and meta analysis
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