Developmentally acquired PKA localisation in mouse oocytes and embryos.

Localisation of Protein Kinase A (PKA) by A-Kinase Anchoring Proteins (AKAPs) is known to coordinate localised signalling complexes that target cAMP-mediated signalling to specific cellular sub-domains. The cAMP PKA signalling pathway is implicated in both meiotic arrest and meiotic resumption, thus...

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Autori principali: Webb, R, Tinworth, L, Thomas, G, Zaccolo, M, Carroll, J
Natura: Journal article
Lingua:English
Pubblicazione: 2008