Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium.

Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium.

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Citrobacter rodentium, an attaching-effacing bacterial pathogen, establishes an acute infection of the murine colonic epithelium and induces a mild colitis in immunocompetent mice. This study describes the role of T-cell subsets and B lymphocytes in immunity to C. rodentium. C57Bl/6 mice orally infe...

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Main Authors:	Simmons, C, Clare, S, Ghaem-Maghami, M, Uren, T, Rankin, J, Huett, A, Goldin, R, Lewis, D, MacDonald, T, Strugnell, R, Frankel, G, Dougan, G
格式:	Journal article
语言:	English
出版:	2003

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