A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity.
Nicotine is the principal addictive component in tobacco, and following uptake acts in the central nervous system. The smoking-cessation efforts of most smokers fail because a single slip often delivers sufficient nicotine to the brain to reinstate the drug-seeking behaviour. Blocking nicotine from...
| Główni autorzy: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
2005
|