Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity

Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity

Sepsis results in elevated adenosine in circulation. Extracellular adenosine triggers immunosuppressive signaling via the A2a receptor (A2aR). Sepsis survivors develop persistent immunosuppression with increased risk of recurrent infections. We utilized the cecal ligation and puncture (CLP) model of...

Bibliografske podrobnosti
Main Authors:	Nascimento, DC, Viacava, PR, Ferreira, RG, Damaceno, MA, Piñeros, AR, Melo, PH, Donate, PB, Toller-Kawahisa, JE, Zoppi, D, Veras, FP, Peres, RS, Menezes-Silva, L, Caetité, D, Oliveira, AER, Castro, ÍMS, Kauffenstein, G, Nakaya, HI, Borges, MC, Zamboni, DS, Fonseca, DM, Paschoal, JAR, Cunha, TM, Quesniaux, V, Linden, J, Cunha, FQ, Ryffel, B, Alves-Filho, JC
Format:	Journal article
Jezik:	English
Izdano:	Cell Press 2021

Podobne knjige/članki

NEUTROPHIL PD-L1+ IS INVOLVED IN THE EXACERBATION SIGNATURE OF THE HYPERINFLAMMATORY PHENOTYPE SEPTIC RESPONSE
od: GCM Cebinelli, et al.
Izdano: (2024-10-01)

Plasmablastic Lymphoma
od: Subecha Bhusal, et al.
Izdano: (2017-07-01)

Plasmablastic lymphoma in Malawi
od: Takondwa Zuze, et al.
Izdano: (2018-06-01)

Plasmablasts and neuroimmunological disorders
od: Norio Chihara, et al.
Izdano: (2019-07-01)

Two Cases of Plasmablastic Myeloma Mimicking Plasmablastic Lymphoma With In‐Depth Review of Literature
od: Sakiko Kitamura, et al.
Izdano: (2025-02-01)

Plasmablastic Lymphoma or Plasmablastic Myeloma: A Case of Post-Transplant Lymphoproliferative Disorder
od: Poornima Ramadas, et al.
Izdano: (2021-01-01)

Circulating plasmablasts in dengue fever
od: Robert Noble, et al.
Izdano: (2024-10-01)

Plasmablastic Lymphoma: A Systematic Review
od: Jorge J. Castillo, et al.
Izdano: (2011-01-01)

Plasmablastic Lymphoma Mimicking Acute Pancreatitis
od: Faisal Inayat, et al.
Izdano: (2016-01-01)

Plasmablastic lymphoma: one or more tumors?
od: Stefano A. Pileri, et al.
Izdano: (2021-05-01)

Plasmablastic Myeloma- A Diagnostic Dilemma
od: Shiva Kumar Komaravelli, et al.
Izdano: (2023-05-01)

Plasmablastic lymphoma masked by hidradenitis suppurativa
od: Sarah Preis, MD, et al.
Izdano: (2022-09-01)

Anaplastic: Plasmablastic plasmacytoma of the vocal cord
od: Andleeb Abrari, et al.
Izdano: (2014-01-01)

How neutrophil metabolism affects bacterial killing
od: Juliana E. Toller-Kawahisa, et al.
Izdano: (2022-11-01)

Impact of highly active antiretroviral therapy in the development and remission of oral plasmablastic lymphoma
od: Vivian Petersen Wagner, et al.
Izdano: (2016-01-01)

Plasmablastic lymphoma in HIV+ patients: an expanding spectrum.
od: Chetty, R, et al.
Izdano: (2003)

CURRENT KNOWLEDGE ON HIV-ASSOCIATED PLASMABLASTIC LYMPHOMA
od: Michele Bibas, et al.
Izdano: (2014-10-01)

Intraocular Plasmablastic Lymphoma in a HIV Patient
od: Carolline Fontes Alves Mariano, et al.
Izdano: (2017-01-01)

Phenogenomic heterogeneity of post-transplant plasmablastic lymphomas
od: Rebecca J. Leeman-Neill, et al.
Izdano: (2020-12-01)

Plasmablastic lymphoma: current knowledge and future directions
od: Ji-Wei Li, et al.
Izdano: (2024-02-01)

Plasmablastic lymphoma with skin involvement in an immunocompetent male
od: Baixue Lv, et al.
Izdano: (2023-12-01)

Plasmablastic myeloma progressed to plasma cell leukaemia
od: Ke Xu, et al.
Izdano: (2021-11-01)

Chronic lymphocytic leukaemia with concomitant plasmablastic lymphoma
od: Jacqueline Goedhals, et al.
Izdano: (2017-03-01)

An unusual case of plasmablastic lymphoma presenting as dermatomyositis
od: Ashlyn Rui Yin Chee, et al.
Izdano: (2020-05-01)

Pathogen-specific circulating plasmablasts in patients with pneumonia.
od: Nina V Palkola, et al.
Izdano: (2012-01-01)

Oral plasmablastic lymphoma as the first manifestation of AIDS
od: Daniela Assis do Vale, et al.
Izdano: (2017-01-01)

Pediatric plasmablastic lymphoma: Diagnostic and therapeutic dilemma
od: Aroonima Misra, et al.
Izdano: (2017-01-01)

PLASMABLASTIC LYMPHOMA. A STATE-OF-THE-ART REVIEW (1)
od: Michele Bibas
Izdano: (2024-01-01)

Oral plasmablastic lymphoma: at the origin of the discovery of an HIV infection
od: Rahman Nurhayu Ab, et al.
Izdano: (2024-01-01)

Testicular plasmablastic lymphoma in a HIV-negative patient
od: Dong Wang, et al.
Izdano: (2025-01-01)

Radiological-Pathological Correlation in Plasmablastic Lymphoma in an Immunocompromised Patient
od: A. Moramarco, et al.
Izdano: (2018-01-01)

MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma
od: Joan Enric Ramis-Zaldivar, et al.
Izdano: (2021-05-01)

IgE+ plasmablasts predict the onset of clinical allergy
od: Elisabeth M. Simonin, et al.
Izdano: (2023-02-01)

Plasmablastic Lymphoma of the Maxillary Sinus Causing Orbital Complication
od: Sedat Aydın, et al.
Izdano: (2018-09-01)

Plasmablastic lymphoma with initial presentation in the skin in an old patient
od: Yi-Hsuan Hu, et al.
Izdano: (2019-01-01)

Plasmablastic lymphoma presenting as a ureteral polypoid mass
od: Sohei Yamamoto, et al.
Izdano: (2018-01-01)

Plasmablastic lymphoma presenting with ileocecal intussusception in an immunocompetent patient
od: Ok Ran Shin, et al.
Izdano: (2020-07-01)

Myelomatous Pleural Effusion in a Relapse Plasmablastic Myeloma
od: Prachi Tripathi, et al.
Izdano: (2021-06-01)

EBV infection determines the immune hallmarks of plasmablastic lymphoma
od: Pauline Gravelle, et al.
Izdano: (2018-10-01)

Plasmablastic lymphoma in epstein–Barr virus-negative patient
od: Ghaidaa R AlSahari, et al.
Izdano: (2024-01-01)