Mutations in HNF1A result in marked alterations of plasma glycan profile.

A recent genome-wide association study identified hepatocyte nuclear factor 1-α (HNF1A) as a key regulator of fucosylation. We hypothesized that loss-of-function HNF1A mutations causal for maturity-onset diabetes of the young (MODY) would display altered fucosylation of N-linked glycans on plasma pr...

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Үндсэн зохиолчид:	Thanabalasingham, G, Huffman, J, Kattla, J, Novokmet, M, Rudan, I, Gloyn, A, Hayward, C, Adamczyk, B, Reynolds, R, Muzinic, A, Hassanali, N, Pucic, M, Bennett, A, Essafi, A, Polasek, O, Mughal, SA, Redzic, I, Primorac, D, Zgaga, L, Kolcic, I, Hansen, T, Gasperikova, D, Tjora, E, Strachan, M, Nielsen, T
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2013

Mutations in HNF1A result in marked alterations of plasma glycan profile.

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