Altered CD45 expression and disease.
CD45, the leucocyte common antigen, is a haemopoietic cell-specific tyrosine phosphatase. Many isoforms are generated by alternative splicing, but their function remains obscure. The extracellular domain of CD45 is highly polymorphic in all vertebrates. Importantly, human polymorphic variants that a...
Main Authors: | Tchilian, E, Beverley, P |
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Format: | Journal article |
Language: | English |
Published: |
2006
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