Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates
A diastereoselective preparation of -fluoroenones from propargyl acetates has been developed proceeding via a gold-catalyzed rearrangement-fluorination cascade. Control reactions are consistent with a mechanism involving a gold-mediated 3,3-sigmatropic shift followed by a direct, nongold-catalyzed e...
| Prif Awduron: | , , , |
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| Fformat: | Journal article |
| Iaith: | English |
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2010
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| _version_ | 1826260316094201856 |
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| author | Hopkinson, M Giuffredi, G Gee, A Gouverneur, V |
| author_facet | Hopkinson, M Giuffredi, G Gee, A Gouverneur, V |
| author_sort | Hopkinson, M |
| collection | OXFORD |
| description | A diastereoselective preparation of -fluoroenones from propargyl acetates has been developed proceeding via a gold-catalyzed rearrangement-fluorination cascade. Control reactions are consistent with a mechanism involving a gold-mediated 3,3-sigmatropic shift followed by a direct, nongold-catalyzed electrophilic fluorination of the allenyl acetate intermediate. © 2010 Georg Thieme Verlag Stuttgart · New York. |
| first_indexed | 2024-03-06T19:03:41Z |
| format | Journal article |
| id | oxford-uuid:1468b5b0-927d-4214-b402-cba5756705f1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:03:41Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:1468b5b0-927d-4214-b402-cba5756705f12022-03-26T10:19:35ZGold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl AcetatesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1468b5b0-927d-4214-b402-cba5756705f1EnglishSymplectic Elements at Oxford2010Hopkinson, MGiuffredi, GGee, AGouverneur, VA diastereoselective preparation of -fluoroenones from propargyl acetates has been developed proceeding via a gold-catalyzed rearrangement-fluorination cascade. Control reactions are consistent with a mechanism involving a gold-mediated 3,3-sigmatropic shift followed by a direct, nongold-catalyzed electrophilic fluorination of the allenyl acetate intermediate. © 2010 Georg Thieme Verlag Stuttgart · New York. |
| spellingShingle | Hopkinson, M Giuffredi, G Gee, A Gouverneur, V Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title | Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title_full | Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title_fullStr | Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title_full_unstemmed | Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title_short | Gold-Catalyzed Diastereoselective Synthesis of alpha-Fluoroenones from Propargyl Acetates |
| title_sort | gold catalyzed diastereoselective synthesis of alpha fluoroenones from propargyl acetates |
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