A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase.

Triggering of the T cell receptor initiates a signaling cascade resulting in the activation of the T cell. These signals are integrated alongside those resulting from the triggering of other receptors whose function is to modulate the overall response. CD5 is an immunotyrosine-based inhibition motif...

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Autori principali: Bamberger, M, Santos, A, Gonçalves, C, Oliveira, M, James, JR, Moreira, A, Lozano, F, Davis, S, Carmo, A
Natura: Journal article
Lingua:English
Pubblicazione: 2011