Age groups that sustain resurging COVID-19 epidemics in the United States
After initial declines, in mid-2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the United States and Europe. As efforts to control COVID-19 disease are reintensified, understanding the age demographics driving transmission and how these affect the loosening of i...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal article |
| Language: | English |
| Published: |
American Association for the Advancement of Science
2021
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| _version_ | 1826312626221613056 |
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| author | Monod, M Blenkinsop, A Xi, X Hebert, D Bershan, S Tietze, S Baguelin, M Bradley, VC Chen, Y Coupland, H Filippi, S Ish-Horowicz, J McManus, M Mellan, T Gandy, A Hutchinson, M Unwin, HJT van Elsland, SL Vollmer, MAC Weber, S Zhu, H Bezancon, A Ferguson, NM Mishra, S Flaxman, S Bhatt, S Ratmann, O |
| author2 | Imperial College COVID-19 Response Team |
| author_facet | Imperial College COVID-19 Response Team Monod, M Blenkinsop, A Xi, X Hebert, D Bershan, S Tietze, S Baguelin, M Bradley, VC Chen, Y Coupland, H Filippi, S Ish-Horowicz, J McManus, M Mellan, T Gandy, A Hutchinson, M Unwin, HJT van Elsland, SL Vollmer, MAC Weber, S Zhu, H Bezancon, A Ferguson, NM Mishra, S Flaxman, S Bhatt, S Ratmann, O |
| author_sort | Monod, M |
| collection | OXFORD |
| description | After initial declines, in mid-2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the United States and Europe. As efforts to control COVID-19 disease are reintensified, understanding the age demographics driving transmission and how these affect the loosening of interventions is crucial. We analyze aggregated, age-specific mobility trends from more than 10 million individuals in the United States and link these mechanistically to age-specific COVID-19 mortality data. We estimate that as of October 2020, individuals aged 20 to 49 are the only age groups sustaining resurgent SARS-CoV-2 transmission with reproduction numbers well above one and that at least 65 of 100 COVID-19 infections originate from individuals aged 20 to 49 in the United States. Targeting interventions-including transmission-blocking vaccines-to adults aged 20 to 49 is an important consideration in halting resurgent epidemics and preventing COVID-19-attributable deaths. |
| first_indexed | 2024-04-09T03:57:22Z |
| format | Journal article |
| id | oxford-uuid:14c23e47-f759-4b16-9959-e0f18dfc5470 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-04-09T03:57:22Z |
| publishDate | 2021 |
| publisher | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | oxford-uuid:14c23e47-f759-4b16-9959-e0f18dfc54702024-03-22T13:57:06ZAge groups that sustain resurging COVID-19 epidemics in the United StatesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:14c23e47-f759-4b16-9959-e0f18dfc5470EnglishSymplectic ElementsAmerican Association for the Advancement of Science2021Monod, MBlenkinsop, AXi, XHebert, DBershan, STietze, SBaguelin, MBradley, VCChen, YCoupland, HFilippi, SIsh-Horowicz, JMcManus, MMellan, TGandy, AHutchinson, MUnwin, HJTvan Elsland, SLVollmer, MACWeber, SZhu, HBezancon, AFerguson, NMMishra, SFlaxman, SBhatt, SRatmann, OImperial College COVID-19 Response TeamAfter initial declines, in mid-2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the United States and Europe. As efforts to control COVID-19 disease are reintensified, understanding the age demographics driving transmission and how these affect the loosening of interventions is crucial. We analyze aggregated, age-specific mobility trends from more than 10 million individuals in the United States and link these mechanistically to age-specific COVID-19 mortality data. We estimate that as of October 2020, individuals aged 20 to 49 are the only age groups sustaining resurgent SARS-CoV-2 transmission with reproduction numbers well above one and that at least 65 of 100 COVID-19 infections originate from individuals aged 20 to 49 in the United States. Targeting interventions-including transmission-blocking vaccines-to adults aged 20 to 49 is an important consideration in halting resurgent epidemics and preventing COVID-19-attributable deaths. |
| spellingShingle | Monod, M Blenkinsop, A Xi, X Hebert, D Bershan, S Tietze, S Baguelin, M Bradley, VC Chen, Y Coupland, H Filippi, S Ish-Horowicz, J McManus, M Mellan, T Gandy, A Hutchinson, M Unwin, HJT van Elsland, SL Vollmer, MAC Weber, S Zhu, H Bezancon, A Ferguson, NM Mishra, S Flaxman, S Bhatt, S Ratmann, O Age groups that sustain resurging COVID-19 epidemics in the United States |
| title | Age groups that sustain resurging COVID-19 epidemics in the United States |
| title_full | Age groups that sustain resurging COVID-19 epidemics in the United States |
| title_fullStr | Age groups that sustain resurging COVID-19 epidemics in the United States |
| title_full_unstemmed | Age groups that sustain resurging COVID-19 epidemics in the United States |
| title_short | Age groups that sustain resurging COVID-19 epidemics in the United States |
| title_sort | age groups that sustain resurging covid 19 epidemics in the united states |
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