CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression.

CD147 is a broadly expressed plasma membrane glycoprotein containing two immunoglobulin-like domains and a single charge-containing transmembrane domain. Here we use co-immunoprecipitation and chemical cross-linking to demonstrate that CD147 specifically interacts with MCT1 and MCT4, two members of...

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Détails bibliographiques
Auteurs principaux: Kirk, P, Wilson, M, Heddle, C, Brown, M, Barclay, N, Halestrap, A
Format: Conference item
Publié: 2000