The UK Biobank resource with deep phenotyping and genomic data

The UK Biobank resource with deep phenotyping and genomic data

The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment. The open resource is unique in its size and scope. A rich variety of phenotypic and health-...

Bibliografske podrobnosti
Main Authors:	Bycroft, C, Freeman, C, Petkova, D, Band, G, Elliott, L, Sharp, K, Motyer, A, Vukcevic, D, Delaneau, O, O'Connell, J, Cortes, A, Welsh, S, Young, A, Effingham, M, McVean, G, Leslie, S, Allen, N, Donnelly, P, Marchini, J
Format:	Journal article
Jezik:	English
Izdano:	Nature Publishing Group 2018

Podobne knjige/članki

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
od: Cortes, A, et al.
Izdano: (2017)

Haplotype estimation for biobank-scale data sets
od: O'Connell, J, et al.
Izdano: (2016)

A statistical method for predicting classical HLA alleles from SNP data.
od: Leslie, S, et al.
Izdano: (2008)

A model-based approach to capture genetic variation for future association studies.
od: Eyheramendy, S, et al.
Izdano: (2007)

A common sequence motif associated with recombination hot spots and genome instability in humans.
od: Myers, S, et al.
Izdano: (2008)

A common sequence motif associated with recombination hot spots and genome instability in humans.
od: Myers, S, et al.
Izdano: (2008)

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.
od: Cortes, A, et al.
Izdano: (2019)

A new multipoint method for genome-wide association studies by imputation of genotypes.
od: Marchini, J, et al.
Izdano: (2007)

A fine-scale map of recombination rates and hotspots across the human genome.
od: Myers, S, et al.
Izdano: (2005)

The distribution and causes of meiotic recombination in the human genome.
od: Myers, S, et al.
Izdano: (2006)

Genome-wide association studies of brain imaging phenotypes in UK Biobank
od: Elliott, L, et al.
Izdano: (2018)

Phasing for medical sequencing using rare variants and large haplotype reference panels
od: Sharp, K, et al.
Izdano: (2016)

Right hemisphere stroke is linked to reduced social connectedness in the UK Biobank cohort
od: Katherine O’Connell, et al.
Izdano: (2024-11-01)

Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel.
od: Delaneau, O, et al.
Izdano: (2014)

HLA*IMP - an integrated framework for imputing classical HLA alleles from SNP genotypes
od: Dilthey, A, et al.
Izdano: (2011)

Interrogating genetic variation in the HLA using high throughput technologies
od: McVean, G, et al.
Izdano: (2012)

HLA*IMP--an integrated framework for imputing classical HLA alleles from SNP genotypes.
od: Dilthey, A, et al.
Izdano: (2011)

Identification of host-pathogen-disease relationships using a scalable Multiplex Serology platform in UK Biobank
od: Mentzer, A, et al.
Izdano: (2022)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
od: Myers, S, et al.
Izdano: (2010)

The structure of linkage disequilibrium around a selective sweep.
od: McVean, G
Izdano: (2007)

Evolutionary genetics: what is driving male mutation?
od: McVean, G
Izdano: (2000)

What drives recombination hotspots to repeat DNA in humans?
od: McVean, G
Izdano: (2010)

A genealogical interpretation of principal components analysis.
od: McVean, G
Izdano: (2009)

Linkage Disequilibrium, Recombination and Selection
od: McVean, G
Izdano: (2008)

Parent-of-Origin inference for biobanks
od: Robin J. Hofmeister, et al.
Izdano: (2022-11-01)

The advantages of UK Biobank's open‐access strategy for health research
od: Conroy, M, et al.
Izdano: (2019)

Scanning the human genome for signals of selection.
od: McVean, G, et al.
Izdano: (2006)

Estimating diversifying selection and functional constraint in the presence of recombination.
od: Wilson, D, et al.
Izdano: (2006)

Estimating recombination rates from genetic variation in humans.
od: Auton, A, et al.
Izdano: (2012)

Recombination rate estimation in the presence of hotspots.
od: Auton, A, et al.
Izdano: (2007)

Bayesian meta‐analysis across genome‐wide association studies of diverse phenotypes
od: Trochet, H, et al.
Izdano: (2019)

PRDM9 marks the spot.
od: McVean, G, et al.
Izdano: (2010)

The comings and goings of a Y polymorphism.
od: Tyler-Smith, C, et al.
Izdano: (2003)

UK biobank: enhanced assessment of the epidemiology and long-term impact of coronavirus disease-2019
od: Feng, Q, et al.
Izdano: (2023)

Improved whole-chromosome phasing for disease and population genetic studies.
od: Delaneau, O, et al.
Izdano: (2013)

A linear complexity phasing method for thousands of genomes
od: Delaneau, O, et al.
Izdano: (2012)

A linear complexity phasing method for thousands of genomes.
od: Delaneau, O, et al.
Izdano: (2012)

Joint Genotype Calling With Array and Sequence Data
od: O'Connell, J, et al.
Izdano: (2012)

Joint genotype calling with array and sequence data.
od: O'Connell, J, et al.
Izdano: (2012)

Germs, genomes and genealogies.
od: Wilson, D, et al.
Izdano: (2005)