Targeting intracellular mediators of pattern-recognition receptor signalling to adjuvant vaccination.
PRR (pattern-recognition receptor) signalling is involved early in the immune response and therefore would be attractive to target during vaccination. The use of PRR ligands has shown some success; however, toxicity and non-specificity are issues with this strategy. The targeting of PRR intracellula...
Автори: | Wales, J, Andreakos, E, Feldmann, M, Foxwell, B |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2007
|
Схожі ресурси
Схожі ресурси
-
Targeting intracellular mediators of pattern-recognition receptor signalling to adjuvant vaccination
за авторством: Wales, J, та інші
Опубліковано: (2007) -
Targeting intracellular signaling: a novel approach to vaccination.
за авторством: Wales, J, та інші
Опубліковано: (2007) -
Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
за авторством: Andreakos, E, та інші
Опубліковано: (2006) -
Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?
за авторством: Andreakos, E, та інші
Опубліковано: (2004) -
Endotoxin signaling in human macrophages: signaling via an alternate mechanism.
за авторством: Sacre, S, та інші
Опубліковано: (2004)