Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells

Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells

CAPSULE SUMMARY: Out of all type-2 immune cells, only ILC2s withstand corticosteroid treatment due to a reduced pro-apoptotic machinery. The findings may advance the understanding on the mechanism in steroid-resistant diseases and facilitate the development of improved therapies.

Detalhes bibliográficos
Main Authors: Luo, J, Wu, Y, Shrimanker, R, Go, S, Ye, Y, Hardman, C, Nahler, J, Chen, Y, Stöger, L, Zeng, N, Liu, W, Reed, L, Tolkovsky, A, Klenerman, P, Ogg, G, Pavord, I, Xue, L
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2019

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