GluR-A-dependent synaptic plasticity is required for the temporal encoding of nonspatial information.
Four related experiments studied operant performance of mice on differential reinforcement of low rates of responding (DRL) paradigms. Experiment 1 showed that excitotoxic hippocampal lesions impaired performance of a 10-s DRL schedule (DRL-10). Experiments 2 and 3 showed that GluR-A AMPA receptor s...
Autori principali: | Reisel, D, Bannerman, D, Deacon, R, Sprengel, R, Seeburg, P, Rawlins, J |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2005
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