JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.

JMY is a p300-binding protein with dual action: by enhancing P53 transcription in the nucleus, it plays an important role in the cellular response to DNA damage, while by promoting actin filament assembly in the cytoplasm; it induces cell motility in vitro. Therefore, it has been argued that, depend...

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Dettagli Bibliografici
Autori principali:	Adighibe, O, Turley, H, Leek, R, Harris, A, Coutts, A, La Thangue, N, Gatter, K, Pezzella, F
Natura:	Journal article
Lingua:	English
Pubblicazione:	Springer Verlag 2014

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