Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma

Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma

Abstract Sequencing studies of Diffuse Large B Cell Lymphoma (DLBCL) have identified hundreds of recurrently altered genes. However, it remains largely unknown whether and how these mutations may contribute to lymphomagenesis, either individually or in combination. Existing strategies to address thi...

Bibliografiset tiedot
Päätekijät:	Caeser, R, Di Re, M, Krupka, J, Gao, J, Lara-Chica, M, Dias, JML, Cooke, S, Fenner, R, Usheva, Z, Runge, H, Beer, P, Eldaly, H, Pak, H-K, Park, C-S, Vassiliou, GS, Huntly, BJP, Mupo, A, Bashford-Rogers, RJM, Hodson, D
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	Nature Research 2019

Samankaltaisia teoksia

Genetic modification of primary human B cells to model high-grade lymphoma
Tekijä: Caeser, R, et al.
Julkaistu: (2019)

Genetic modification of primary human B cells to model high-grade lymphoma
Tekijä: Rebecca Caeser, et al.
Julkaistu: (2019-10-01)

Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
Tekijä: Teng, YHF, et al.
Julkaistu: (2021)

Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data
Tekijä: Pernes, JI, et al.
Julkaistu: (2024)

The B cell immunobiology that underlies CNS autoantibody-mediated diseases
Tekijä: Sun, B, et al.
Julkaistu: (2020)

Early loss of CREBBP confers malignant stem cell properties on lymphoid progenitors
Tekijä: Huntly, B, et al.
Julkaistu: (2016)

Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones
Tekijä: Bashford-Rogers, R, et al.
Julkaistu: (2016)

Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development
Tekijä: Burrows, N, et al.
Julkaistu: (2020)

Double-jeopardy: scRNA-seq doublet/multiplet detection using multi-omic profiling
Tekijä: Sun, B, et al.
Julkaistu: (2021)

Antibody repertoire analysis in polygenic autoimmune diseases
Tekijä: Bashford-Rogers, R, et al.
Julkaistu: (2018)

THE EXPERIENCE OF HIGHER SCHOOL STUDENTS’ SOCIALIZATION: INTROSPECTIVE APPROACH
Tekijä: T. F. Usheva
Julkaistu: (2015-09-01)

Combined influence of B-cell receptor rearrangement and somatic hypermutation on B-cell class-switch fate in health and in chronic lymphocytic leukemia
Tekijä: Petrova, V, et al.
Julkaistu: (2018)

Anaesthesia for the geriatric dog and cat
Tekijä: Hughes JML
Julkaistu: (2008-06-01)

Relevance of human fat distribution on lipid and lipoprotein metabolism and cardiovascular disease risk
Tekijä: Piché, M, et al.
Julkaistu: (2018)

Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse
Tekijä: Bashford-Rogers, R, et al.
Julkaistu: (2016)

The temporal binding window between ICMS and vision depends on biological relevance of visual stimuli
Tekijä: Isabelle Rosenthal, et al.
Julkaistu: (2023-01-01)

SPECIFICS OF DEVELOPING REFLECTIVE SKILLS OF STUDENTS MAJORING IN PEDAGOGICS
Tekijä: Tatyana F. Usheva
Julkaistu: (2024-10-01)

Talent Management in Modern Human Resources Management
Tekijä: M.N. Usheva
Julkaistu: (2011-10-01)

Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice
Tekijä: Oliver M. Dovey, et al.
Julkaistu: (2016-08-01)

Painting in mixed media : practical advice and exiting ideas for combining painting media /
Tekijä: 447091 Huntly, Moira
Julkaistu: (1989)

Deception in network defences using unpredictability
Tekijä: Happa, J, et al.
Julkaistu: (2021)

Deep HDR Hallucination for Inverse Tone Mapping
Tekijä: Demetris Marnerides, et al.
Julkaistu: (2021-06-01)

Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution
Tekijä: Grove, C, et al.
Julkaistu: (2016)

Influence of the presence of children taken care of in work motivation
Tekijä: Usheva Mariana, et al.
Julkaistu: (2020-01-01)

Earnings Management as a Tool of Bankruptcy Prevention during Global Pandemic of COVID-19
Tekijä: Usheva Mariana, et al.
Julkaistu: (2021-01-01)

Rendering Interior Cultural Heritage Scenes Using Image−Based Shooting
Tekijä: Happa, J, et al.
Julkaistu: (2011)

Ultrasensitive amplicon barcoding for next-generation sequencing facilitating sequence error and amplification-bias correction
Tekijä: Ahmed, I, et al.
Julkaistu: (2020)

Shared D-J rearrangements reveal cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL: Response to Abdo, C. et al 2020
Tekijä: Bueno, C, et al.
Julkaistu: (2020)

The current understanding of the phenotypic and functional properties of human regulatory B cells (Bregs)
Tekijä: Ahsan, NF, et al.
Julkaistu: (2024)

New geographic records of Hamlets, Hypoplectrus spp. (Serranidae), in the Caribbean Sea
Tekijä: Ernest H Williams, Jr, et al.
Julkaistu: (2006-12-01)

Advancing pneumonia virus drug discovery with virtual screening: A cutting-edge fast and resource efficient machine learning framework for predictive analysis
Tekijä: Ochin Sharma, et al.
Julkaistu: (2024-01-01)

Enhancement, disability and the riddle of the relevant circumstances
Tekijä: Zohny, H
Julkaistu: (2016)

Research on the Relevancy of Scientific Literature Based on the Citation-Mention Frequency
Tekijä: Guang Yu, et al.
Julkaistu: (2019-01-01)

Anomaly detection using pattern-of-life visual metaphors
Tekijä: Happa, J, et al.
Julkaistu: (2019)

SOCIAL ADAPTATION OF MIGRANT CHILDREN IN GENERAL SCHOOL
Tekijä: T. F. Usheva, et al.
Julkaistu: (2019-12-01)

The relevance of reducing Veress needle overshooting
Tekijä: T. Horeman-Franse, et al.
Julkaistu: (2023-10-01)

Fear conditioning to subliminal fear relevant and non fear relevant stimuli.
Tekijä: Ottmar V Lipp, et al.
Julkaistu: (2014-01-01)

Optimizing communication between the radiologist and the general practitioner
Tekijä: LBO Jans, et al.
Julkaistu: (2013-11-01)

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.
Tekijä: Neubauer, S, et al.
Julkaistu: (2013)

CRH receptor genetic variation in a developmental primate model relevant to the risk to develop anxiety and depression
Tekijä: Ned H. Kalin, et al.
Julkaistu: (2012-09-01)