Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma
Abstract Sequencing studies of Diffuse Large B Cell Lymphoma (DLBCL) have identified hundreds of recurrently altered genes. However, it remains largely unknown whether and how these mutations may contribute to lymphomagenesis, either individually or in combination. Existing strategies to address thi...
| Autors principals: | , , , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
Nature Research
2019
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