Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

When applied extracellularly, myo-inositol hexakisphosphate (InsP 6) and myo-inositol pentakisphosphate (InsP5) can inhibit the growth and proliferation of tumour cells. There is debate about whether these effects result from interactions of InsP6 and InsP5 with intracellular or extracellular target...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Riley, A, Windhorst, S, Lin, H, Potter, B
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Wiley 2013

Những quyển sách tương tự

Effect of Phytate (InsP6) and Other Inositol-Phosphates (InsP5, InsP4, InsP3, InsP2) on Crystallization of Calcium Oxalate, Brushite, and Hydroxyapatite
Bằng: Paula Calvó, et al.
Được phát hành: (2023-06-01)

Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP5
Bằng: Shipton, ML, et al.
Được phát hành: (2023)

The Binding Mechanism Between Inositol Phosphate (InsP) and the Jasmonate Receptor Complex: A Computational Study
Bằng: Mengqi Cui, et al.
Được phát hành: (2018-07-01)

Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia–reperfusion injury by elevating plasma adiponectin
Bằng: Fu, L, et al.
Được phát hành: (2024)

Synthetic tools for studying the chemical biology of InsP8
Bằng: Riley, A, et al.
Được phát hành: (2015)

Synthetic tools for studying the chemical biology of InsP8
Bằng: Riley, A, et al.
Được phát hành: (2015)

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase
Bằng: Riley, A, et al.
Được phát hành: (2012)

Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP<sub>7</sub>
Bằng: Soumyadip Sahu, et al.
Được phát hành: (2023-01-01)

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7
Bằng: Riley, A, et al.
Được phát hành: (2019)

Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels.
Bằng: Chunfang Gu, et al.
Được phát hành: (2016-01-01)

Synthesis of D-myo-inositol 1,4,5-trisphosphate (InsP3) derivatives via a novel Ferrier rearrangement
Bằng: Keddie, N, et al.
Được phát hành: (2008)

Complexes of myo-inositol-hexakisphosphate (InsP6) with zinc or lanthanum to enhance excretion of radioactive strontium from the body.
Bằng: Kazuma Ogawa, et al.
Được phát hành: (2018-01-01)

Novel model of calcium and inositol 1,4,5-trisphosphate regulation of InsP3 receptor channel gating in native endoplasmic reticulum
Bằng: J. Kevin Foskett, et al.
Được phát hành: (2004-01-01)

Patterns of gene expression in Drosophila InsP3 receptor mutant larvae reveal a role for InsP3 signaling in carbohydrate and energy metabolism.
Bằng: Satish Kumar, et al.
Được phát hành: (2011-01-01)

Cytosolic [Ca2+] regulation of InsP3-evoked puffs.
Bằng: Yamasaki-Mann, M, et al.
Được phát hành: (2013)

Simple synthesis of 32P-labelled inositol hexakisphosphates for study of phosphate transformations
Bằng: Whitfield, H, et al.
Được phát hành: (2017)

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate
Bằng: Riley, A, et al.
Được phát hành: (2018)

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.
Bằng: Kasri, N, et al.
Được phát hành: (2004)

Inositol Phosphates and Retroviral Assembly: A Cellular Perspective
Bằng: Clifton L. Ricaña, et al.
Được phát hành: (2021-12-01)

The role of Ca2+ signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
Bằng: Dan Pan, et al.
Được phát hành: (2024-12-01)

Spatially defined InsP3-mediated signaling in embryonic stem cell-derived cardiomyocytes.
Bằng: Nidhi Kapoor, et al.
Được phát hành: (2014-01-01)

Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia
Bằng: Manivannan Subramanian, et al.
Được phát hành: (2013-05-01)

Polyphenolic extract of InsP 5-ptase expressing tomato plants reduce the proliferation of MCF-7 breast cancer cells.
Bằng: Mohammad Alimohammadi, et al.
Được phát hành: (2017-01-01)

Improved visualisation of internalised carbon nanotubes by maximising cell spreading on nanostructured substrates
Bằng: Chenchen Bao, et al.
Được phát hành: (2010-12-01)

Role of Inositols and Inositol Phosphates in Energy Metabolism
Bằng: Saimai Chatree, et al.
Được phát hành: (2020-11-01)

Bioactivity of Inositol Phosphates
Bằng: Ivana Vucenik
Được phát hành: (2021-08-01)

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
Bằng: Watson, P, et al.
Được phát hành: (2016)

MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU
Bằng: Riley Payne, et al.
Được phát hành: (2017-12-01)

ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein
Bằng: Horia Vais, et al.
Được phát hành: (2020-05-01)

Single-molecule fluorescence of internalised biomolecules in live bacteria
Bằng: Plochowietz, A
Được phát hành: (2012)

Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis
Bằng: Samuel E. Weinberg, et al.
Được phát hành: (2020-12-01)

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors
Bằng: Rossi, A, et al.
Được phát hành: (2010)

Increased InsP3Rs in the junctional sarcoplasmic reticulum augment Ca2+ transients and arrhythmias associated with cardiac hypertrophy.
Bằng: Harzheim, D, et al.
Được phát hành: (2009)

One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP<sub>8</sub> Occurs under Cytosolic Conditions
Bằng: Leonie Kurz, et al.
Được phát hành: (2023-04-01)

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
Bằng: Peter J. Watson, et al.
Được phát hành: (2016-04-01)

Inositol hexakisphosphate increases the size of platelet aggregates
Bằng: Brehm, M, et al.
Được phát hành: (2018)

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels
Bằng: Whitfield, H, et al.
Được phát hành: (2020)

Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives.
Bằng: Conway, S, et al.
Được phát hành: (2007)

Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling
Bằng: Jia Yu, et al.
Được phát hành: (2023-05-01)

A fluorescent probe identifies active site ligands of inositol pentakisphosphate 2-kinase
Bằng: Whitfield, H, et al.
Được phát hành: (2018)