Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

We conducted a genome-wide association study to identify novel associations between genetic variants and circulating plasminogen activator inhibitor-1 (PAI-1) concentration, and examined functional implications of variants and genes that were discovered. A discovery meta-analysis was performed in 19...

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Bibliographic Details
Main Authors: Huang, J, Sabater-Lleal, M, Asselbergs, F, Tregouet, D, Shin, S, Ding, J, Baumert, J, Oudot-Mellakh, T, Folkersen, L, Johnson, A, Smith, N, Williams, S, Ikram, M, Kleber, M, Becker, D, Truong, V, Mychaleckyj, J, Tang, W, Yang, Q, Sennblad, B, Moore, J, Williams, F, Dehghan, A, Silbernagel, G, Schrijvers, E
Format: Journal article
Language:English
Published: 2012

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