Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications.
Phosphorus magnetic resonance spectroscopy (31P-MRS) has revealed a lot about the biochemistry of physiological and pathological processes in the heart. Nevertheless, until today, cardiac 31P-MRS has not had any clinical impact, albeit some pioneering studies demonstrated that 31P-MRS can indeed pro...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2001
|
| _version_ | 1826260469232435200 |
|---|---|
| author | von Kienlin, M Beer, M Greiser, A Hahn, D Harre, K Köstler, H Landschütz, W Pabst, T Sandstede, J Neubauer, S |
| author_facet | von Kienlin, M Beer, M Greiser, A Hahn, D Harre, K Köstler, H Landschütz, W Pabst, T Sandstede, J Neubauer, S |
| author_sort | von Kienlin, M |
| collection | OXFORD |
| description | Phosphorus magnetic resonance spectroscopy (31P-MRS) has revealed a lot about the biochemistry of physiological and pathological processes in the heart. Nevertheless, until today, cardiac 31P-MRS has not had any clinical impact, albeit some pioneering studies demonstrated that 31P-MRS can indeed provide diagnostic information. In this paper, the development of techniques for human cardiac 31P-MRS over the past decade is reviewed, and the requirements for a reliable clinical measurement protocol are discussed. Spatial localization with optimal pointspread function (SLOOP) is a new method to achieve spatial localization and absolute quantitation. Its properties are detailed, and preliminary findings in patients with dilated cardiomyopathy or myocardial infarction are presented. |
| first_indexed | 2024-03-06T19:06:08Z |
| format | Journal article |
| id | oxford-uuid:1533ab93-b1ee-47a0-85a0-7035a0289127 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:06:08Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:1533ab93-b1ee-47a0-85a0-7035a02891272022-03-26T10:24:09ZAdvances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1533ab93-b1ee-47a0-85a0-7035a0289127EnglishSymplectic Elements at Oxford2001von Kienlin, MBeer, MGreiser, AHahn, DHarre, KKöstler, HLandschütz, WPabst, TSandstede, JNeubauer, SPhosphorus magnetic resonance spectroscopy (31P-MRS) has revealed a lot about the biochemistry of physiological and pathological processes in the heart. Nevertheless, until today, cardiac 31P-MRS has not had any clinical impact, albeit some pioneering studies demonstrated that 31P-MRS can indeed provide diagnostic information. In this paper, the development of techniques for human cardiac 31P-MRS over the past decade is reviewed, and the requirements for a reliable clinical measurement protocol are discussed. Spatial localization with optimal pointspread function (SLOOP) is a new method to achieve spatial localization and absolute quantitation. Its properties are detailed, and preliminary findings in patients with dilated cardiomyopathy or myocardial infarction are presented. |
| spellingShingle | von Kienlin, M Beer, M Greiser, A Hahn, D Harre, K Köstler, H Landschütz, W Pabst, T Sandstede, J Neubauer, S Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title | Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title_full | Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title_fullStr | Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title_full_unstemmed | Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title_short | Advances in human cardiac 31P-MR spectroscopy: SLOOP and clinical applications. |
| title_sort | advances in human cardiac 31p mr spectroscopy sloop and clinical applications |
| work_keys_str_mv | AT vonkienlinm advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT beerm advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT greisera advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT hahnd advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT harrek advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT kostlerh advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT landschutzw advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT pabstt advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT sandstedej advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications AT neubauers advancesinhumancardiac31pmrspectroscopysloopandclinicalapplications |