Development of chemical tools to probe the functions of TRIM proteins

Development of chemical tools to probe the functions of TRIM proteins

<p>Epigenetic signalling is regulated by ‘writer’, ‘reader’, and ‘eraser’ proteins, which add, identify and remove histone modifications, respectively. Simultaneous recognition of multiple epigenetic marks by proteins containing tandem reader domains increases the complexity of the information...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Reynolds, J
Awduron Eraill:	Conway, S
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2020
Pynciau:	Organic Chemistry Medicinal Chemistry

Eitemau Tebyg

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Synthesis and mechanistic analyses of boron-containing β-lactamase inhibitors
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Development of tuberculosis imaging probes based on sugars and proteins
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Reaction engineering for protein modification: tools for chemistry and biology
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Site-specific chemical modification of antibodies for the modulation of function
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Selective Quadruple C(sp3)-F Functionalization of Polyfluoroalkyl Ketones
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Design and synthesis of inositol phosphate-based probes
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Femtosecond pump-probe spectroscopy of chemical reactions in liquids and crystals
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Organic and physical chemistry using chemical kinetics : prospects and developments /
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Chemical synthesis and cytotoxicity of neo-glycolipids; rare sugar-glycerol-lipid compounds
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Chemical constituents, antibacterial and antifungal activities of macaranga triloba ( Euphorbiaceae ) /
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Recent developments in one-pot stepwise synthesis (OPSS) of small molecules
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Analysis of potassium (K+) efflux systems (Kef) as an antibiotic target in pathogenic bacteria
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Cyhoeddwyd: (2019)

Design and synthesis of probes for detection of protein-protein interaction and RNA localization
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Journal of the Chemical Society. Section C. Organic chemistry [mikrofilem]
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Mapping the synapse : synthesis and validation of chemical probes for interrogating PDZ domains
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Detailed chemical and spectroscopic probes of the multicopper active sites in Rhus laccase
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Cyhoeddwyd: (2021)

Chemical tools to probe the role of bromodomains in the parasite Trypanosoma cruzi
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