Detection of vaccine-induced antibodies to Ebola virus in oral fluid

Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected i...

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Main Authors: Lambe, T, Rampling, T, Samuel, D, Bowyer, G, Ewer, K, Venkatraman, N, Edmans, M, Dicks, S, Hill, A, Tedder, R, Gilbert, S
Format: Journal article
Language:English
Published: Oxford University Press 2016
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author Lambe, T
Rampling, T
Samuel, D
Bowyer, G
Ewer, K
Venkatraman, N
Edmans, M
Dicks, S
Hill, A
Tedder, R
Gilbert, S
author_facet Lambe, T
Rampling, T
Samuel, D
Bowyer, G
Ewer, K
Venkatraman, N
Edmans, M
Dicks, S
Hill, A
Tedder, R
Gilbert, S
author_sort Lambe, T
collection OXFORD
description Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
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spelling oxford-uuid:15673dd1-fc52-48c5-a5ca-8054da26b3f92022-03-26T10:25:18ZDetection of vaccine-induced antibodies to Ebola virus in oral fluidJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:15673dd1-fc52-48c5-a5ca-8054da26b3f9EnglishSymplectic Elements at OxfordOxford University Press2016Lambe, TRampling, TSamuel, DBowyer, GEwer, KVenkatraman, NEdmans, MDicks, SHill, ATedder, RGilbert, SBlood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
spellingShingle Lambe, T
Rampling, T
Samuel, D
Bowyer, G
Ewer, K
Venkatraman, N
Edmans, M
Dicks, S
Hill, A
Tedder, R
Gilbert, S
Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title_full Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title_fullStr Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title_full_unstemmed Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title_short Detection of vaccine-induced antibodies to Ebola virus in oral fluid
title_sort detection of vaccine induced antibodies to ebola virus in oral fluid
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