Detection of vaccine-induced antibodies to Ebola virus in oral fluid
Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected i...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2016
|
_version_ | 1797055115499143168 |
---|---|
author | Lambe, T Rampling, T Samuel, D Bowyer, G Ewer, K Venkatraman, N Edmans, M Dicks, S Hill, A Tedder, R Gilbert, S |
author_facet | Lambe, T Rampling, T Samuel, D Bowyer, G Ewer, K Venkatraman, N Edmans, M Dicks, S Hill, A Tedder, R Gilbert, S |
author_sort | Lambe, T |
collection | OXFORD |
description | Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875. |
first_indexed | 2024-03-06T19:06:44Z |
format | Journal article |
id | oxford-uuid:15673dd1-fc52-48c5-a5ca-8054da26b3f9 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T19:06:44Z |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | dspace |
spelling | oxford-uuid:15673dd1-fc52-48c5-a5ca-8054da26b3f92022-03-26T10:25:18ZDetection of vaccine-induced antibodies to Ebola virus in oral fluidJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:15673dd1-fc52-48c5-a5ca-8054da26b3f9EnglishSymplectic Elements at OxfordOxford University Press2016Lambe, TRampling, TSamuel, DBowyer, GEwer, KVenkatraman, NEdmans, MDicks, SHill, ATedder, RGilbert, SBlood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875. |
spellingShingle | Lambe, T Rampling, T Samuel, D Bowyer, G Ewer, K Venkatraman, N Edmans, M Dicks, S Hill, A Tedder, R Gilbert, S Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title | Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title_full | Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title_fullStr | Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title_full_unstemmed | Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title_short | Detection of vaccine-induced antibodies to Ebola virus in oral fluid |
title_sort | detection of vaccine induced antibodies to ebola virus in oral fluid |
work_keys_str_mv | AT lambet detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT ramplingt detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT samueld detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT bowyerg detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT ewerk detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT venkatramann detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT edmansm detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT dickss detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT hilla detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT tedderr detectionofvaccineinducedantibodiestoebolavirusinoralfluid AT gilberts detectionofvaccineinducedantibodiestoebolavirusinoralfluid |