ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules

Correct orientation of cell division is considered an important factor for the achievement of normal brain size, as mutations in genes that affect this process are among the leading causes of microcephaly. Abnormal spindle orientation is associated with reduction of the neuronal progenitor symmetric...

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Hlavní autoři: Gai, M, Bianchi, F, Vagnoni, C, Vernì, F, Bonaccorsi, S, Pasquero, S, Berto, G, Sgrò, F, Chiotto, A, Annaratone, L, Sapino, A, Bergo, A, Landsberger, N, Bond, J, Huttner, W, Di Cunto, F
Médium: Journal article
Jazyk:English
Vydáno: EMBO Press 2016