Campath, calcineurin inhibitor reduction and chronic allograft nephropathy (the 3C Study) – results of a randomized controlled clinical trial
Calcineurin inhibitors (CNI e.g. tacrolimus) reduce short-term kidney transplant failure, but chronic nephrotoxicity may contribute to late transplant loss. Elective conversion to inhibitors of the mammalian target of rapamycin pathway (mTOR e.g. sirolimus) might avoid long-term CNI renal damage an...
Main Authors: | Haynes, R, Blackwell, L, Staplin, N, Herrington, W, Emberson, J, Judge, P, Storey, B, Landray, M, Baigent, C, Friend, P |
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Format: | Journal article |
Published: |
Wiley
2018
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