ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID
3-Amino-2-hydroxydecanoic acid (AHDA) is a novel amino acid which has been suggested as the N-terminal component of the recently isolated angiotensin-converting enzyme inhibitor microginin. The naturally occurring amino acid was found to possess syn relative stereochemistry and (2S,3R) absolute ster...
| المؤلفون الرئيسيون: | , , , |
|---|---|
| التنسيق: | Journal article |
| منشور في: |
1995
|
| _version_ | 1826260553101737984 |
|---|---|
| author | Bunnage, M Burke, A Davies, S Goodwin, C |
| author_facet | Bunnage, M Burke, A Davies, S Goodwin, C |
| author_sort | Bunnage, M |
| collection | OXFORD |
| description | 3-Amino-2-hydroxydecanoic acid (AHDA) is a novel amino acid which has been suggested as the N-terminal component of the recently isolated angiotensin-converting enzyme inhibitor microginin. The naturally occurring amino acid was found to possess syn relative stereochemistry and (2S,3R) absolute stereochemistry when the reported 1H and 13C nmr spectroscopic data and the CD data were compared to the spectroscopic data for synthetic (2R,3R)- and (2S,3R)-AHDA. These studies complete the stereochemical assignment of microginin. © 1994. |
| first_indexed | 2024-03-06T19:07:28Z |
| format | Journal article |
| id | oxford-uuid:15a3c645-9001-4939-b0a9-872e512a68b6 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T19:07:28Z |
| publishDate | 1995 |
| record_format | dspace |
| spelling | oxford-uuid:15a3c645-9001-4939-b0a9-872e512a68b62022-03-26T10:26:39ZASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACIDJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:15a3c645-9001-4939-b0a9-872e512a68b6Symplectic Elements at Oxford1995Bunnage, MBurke, ADavies, SGoodwin, C3-Amino-2-hydroxydecanoic acid (AHDA) is a novel amino acid which has been suggested as the N-terminal component of the recently isolated angiotensin-converting enzyme inhibitor microginin. The naturally occurring amino acid was found to possess syn relative stereochemistry and (2S,3R) absolute stereochemistry when the reported 1H and 13C nmr spectroscopic data and the CD data were compared to the spectroscopic data for synthetic (2R,3R)- and (2S,3R)-AHDA. These studies complete the stereochemical assignment of microginin. © 1994. |
| spellingShingle | Bunnage, M Burke, A Davies, S Goodwin, C ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title | ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title_full | ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title_fullStr | ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title_full_unstemmed | ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title_short | ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID |
| title_sort | asymmetric synthesis of the n terminal component of microginin 2s 3r 3 amino 2 hydroxydecanoic acid its 2r 3r epimer and 3r 3 aminodecanoic acid |
| work_keys_str_mv | AT bunnagem asymmetricsynthesisofthenterminalcomponentofmicroginin2s3r3amino2hydroxydecanoicacidits2r3repimerand3r3aminodecanoicacid AT burkea asymmetricsynthesisofthenterminalcomponentofmicroginin2s3r3amino2hydroxydecanoicacidits2r3repimerand3r3aminodecanoicacid AT daviess asymmetricsynthesisofthenterminalcomponentofmicroginin2s3r3amino2hydroxydecanoicacidits2r3repimerand3r3aminodecanoicacid AT goodwinc asymmetricsynthesisofthenterminalcomponentofmicroginin2s3r3amino2hydroxydecanoicacidits2r3repimerand3r3aminodecanoicacid |