Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry.
The structure of the protein tumour necrosis factor (TNF) was determined from crystals of space group P3(1)21 which contain six copies of the TNF monomer per crystallographic asymmetric unit [Jones, Stuart and Walker (1989). Nature (London), 338, 225-228]. The nature of these crystals (relatively hi...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1991
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